{"id":1443,"date":"2017-01-12T13:33:42","date_gmt":"2017-01-12T18:33:42","guid":{"rendered":"http:\/\/monbug.jplaverdure.ca\/fr\/?p=1443"},"modified":"2021-04-11T11:05:15","modified_gmt":"2021-04-11T15:05:15","slug":"reunion-du-mois-de-fevrier","status":"publish","type":"post","link":"https:\/\/monbug.ca\/fr\/reunion-du-mois-de-fevrier\/","title":{"rendered":"R\u00e9union du mois de f\u00e9vrier"},"content":{"rendered":"<p>Auditorium Jacques-Genest, IRCM<br \/>\nMercredi, 25 janiver, 17:00 \u2013 19:00<br \/>\nVous pouvez vous inscrire aux r\u00e9unions sur Meetup,\u00a0<a href=\"http:\/\/www.meetup.com\/monbug\" target=\"_blank\" rel=\"noopener\">http:\/\/www.meetup.com\/monbug<\/a>, ou en envoyant un courriel \u00e0 <a href=\"mailto:inscription@monbug.ca\">inscription@monbug.ca<\/a>.<\/p>\n<p><strong>Agenda<\/strong><\/p>\n<p><strong>17:00 \u2013 17:05 <\/strong>Introduction et annonces communautaires<b><br \/>\n<\/b><strong>17:05 \u2013 17:55<\/strong><b> <\/b>\u00ab\u00a0Epigenome disruption in childhood brain cancer\u00a0\u00bb, Jacek Majewski, PhD, McGill University and Genome Quebec Innovation Centre<b><br \/>\n<\/b><strong>17:55 \u2013 18:10<\/strong><b> <\/b>Pause avec collations et rafra\u00eechissements<b><br \/>\n<\/b><strong>18:10 \u2013 18:40<\/strong> \u00ab\u00a0Algorithms for the validation and correction of orthology relations\u00a0\u00bb, Manuel Lafond, PhD, uOttawa<b><br \/>\n<\/b><strong>18:40 \u2013 19:00<\/strong> Package R \u00ab\u00a0Gviz\u00a0\u00bb, Jean Monlong, MsC, McGill University<\/p>\n<p>Nous allons commencer 2017 en force avec d&rsquo;excellents pr\u00e9sentateurs.<\/p>\n<p>Philip Malric va bri\u00e8vement nous parler du hackathon au mois de mars organis\u00e9 par l&rsquo;Association \u00e9tudiante des bioinformaticiens du cycle sup\u00e9rieurs de l&rsquo;UdeM (AEBINUM).<\/p>\n<p>Dr. Majewski, le pr\u00e9sentateur principal pour la r\u00e9union, iest un profeseur associ\u00e9 au D\u00e9partement de g\u00e9n\u00e9tique humaine de McGill. Il va nous pr\u00e9senter sa recherche sur les perturbations \u00e9pig\u00e9nomiques dans les cancers p\u00e9diatriques du cerveau. Voici un r\u00e9sum\u00e9 de sa pr\u00e9sentation.<\/p>\n<p>\u00ab\u00a0Many cancers are driven by mutations that affect the epigenome: the genetics of epigenetics. For the past few years, we have been studying mutations that directly affect the lysine 27 and 36 residues (k27M and K36M) of the histone H3. Those mutations occur primarily in paediatric cancers, and disrupt the histone trimethylation marks, H3K27me3 and H3K36me3. I will introduce the topic and give some historical background on the discovery and context of those lesions, Then, in more detail, I will talk about our recent work on cell models and functional (epi)genomic profiling of the downstream effects of those mutations on the epigenome and the transcriptome.\u00a0\u00bb<\/p>\n<p>Manuel Lafond, post-doc \u00e0 l&rsquo;Universit\u00e9 d&rsquo;Ottawa dans le laboratoire du Dr. Sankoff, nous pr\u00e9sentera sa recherche sur les algorithmes de validation et correction des relations orthologiques (traduit de l&rsquo;anglais).<\/p>\n<p>Jean Monlong, candidat au doctorat dans le laboratoire du Dr. Bourque, nous pr\u00e9sentera un tutoriel sur le package R, Gviz, utile pour g\u00e9n\u00e9rer des pistes en R.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Auditorium Jacques-Genest, IRCM Mercredi, 25 janiver, 17:00 \u2013 19:00 Vous pouvez vous inscrire aux r\u00e9unions sur Meetup,\u00a0http:\/\/www.meetup.com\/monbug, ou en envoyant un courriel \u00e0 inscription@monbug.ca. Agenda 17:00 \u2013 17:05 Introduction et annonces communautaires 17:05 \u2013 17:55 \u00ab\u00a0Epigenome disruption in childhood brain cancer\u00a0\u00bb, Jacek Majewski, PhD, McGill University and Genome Quebec Innovation Centre 17:55 \u2013 18:10 Pause [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":{"0":"post-1443","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-activites-monbug"},"_links":{"self":[{"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/posts\/1443","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/comments?post=1443"}],"version-history":[{"count":5,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/posts\/1443\/revisions"}],"predecessor-version":[{"id":2028,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/posts\/1443\/revisions\/2028"}],"wp:attachment":[{"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/media?parent=1443"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/categories?post=1443"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/monbug.ca\/fr\/wp-json\/wp\/v2\/tags?post=1443"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}