January - Jacek Majewski, Manuel Lafond, Jean Monlong¶
Event Details
Date/Time:
Wednesday, January 25th, 2017 17h00 - 19h00
Location:
Location: Jacques-Genest auditorium, IRCM
Schedule:
17h00 - 17h05 — Introduction and community announcements
17h05 - 17h55 — Jacek Majewski, PhD (McGill University and Genome Quebec Innovation Centre) — "Epigenome disruption in childhood brain cancer"
17h55 - 18h10 — Break with snacks and refreshments
18h10 - 18h40 — Manuel Lafond, PhD (uOttawa) — "Algorithms for the validation and correction of orthology relations"
18h40 - 19h00 — Jean Monlong, MsC (McGill University) — R package "Gviz"
We're starting 2017 strong with excellent presenters.
Philip Malric will briefly tell us about the hackathon in March organized by the Université de Montréal graduate bioinformatics student association (AEBINUM).
Keynote Speaker: Jacek Majewski, PhD
Affiliation: McGill University and Genome Quebec Innovation Centre
Talk Title: Epigenome disruption in childhood brain cancer
Abstract:
Many cancers are driven by mutations that affect the epigenome: the genetics of epigenetics. For the past few years, we have been studying mutations that directly affect the lysine 27 and 36 residues (K27M and K36M) of the histone H3. Those mutations occur primarily in paediatric cancers, and disrupt the histone trimethylation marks, H3K27me3 and H3K36me3. I will introduce the topic and give some historical background on the discovery and context of those lesions. Then, in more detail, I will talk about our recent work on cell models and functional (epi)genomic profiling of the downstream effects of those mutations on the epigenome and the transcriptome.
Biography
Dr. Majewski is an associate professor in the McGill Department of Human Genetics.
Speaker: Manuel Lafond, PhD
Affiliation: uOttawa
Talk Title: Algorithms for the validation and correction of orthology relations
Biography
Postdoctoral fellow at the University of Ottawa in Dr. Sankoff's laboratory.
Speaker: Jean Monlong, MsC
Affiliation: McGill University
Talk Title: R package "Gviz"
Abstract:
A tutorial on the R package Gviz, useful to generate (genome) tracks in R.
Biography
PhD candidate in Dr. Bourque's laboratory.