March - Mathieu Lajoie, Selin Jessa

Event Details

Date/Time:

Wednesday, March 14th, 2018 17h00 - 18h45

Location:

Location: André-Barbeau room, IRCM

Schedule:

17:00 – 17:05 — Introduction and community announcements
17:05 – 17:45 — “Getting reliable estimates of tumour purity to improve downstream analyses”, Mathieu Lajoie, PhD, Watson lab
17:40 – 18:05 — Break, with snacks and refreshments
18:05 – 18:45 — An introduction to Bioconductor package development, Selin Jessa, Kleinman lab

MonBUG is back with the arrival of spring!

This meeting will be all about R.

Mathieu Lajoie, PhD, will be showing us how he uses R in his genetic analyses. Selin Jessa, author of the R package chromswitch, will be walking us through the steps to submit our own package to Bioconductor, the R repository for bioinformatics packages.

Speaker: Mathieu Lajoie, PhD

Affiliation: Watson lab

Talk Title: Getting reliable estimates of tumour purity to improve downstream analyses

Abstract:

Getting reliable estimates of tumour purity to improve downstream analyses. Solid tumour samples are usually contaminated with a highly variable fraction of infiltrating lymphocytes and stromal cells. In this presentation I will describe different approaches to estimate the cancer cell fraction and discuss how this can impact RNAseq and copy number analysis, using TCGA data. R code snippets included.

Speaker: Selin Jessa

Affiliation: Kleinman lab

Talk Title: An introduction to Bioconductor package development